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Imagezilla set26/7/2023 ![]() However, while the functions of histone modifying enzymes are often linked to epigenetic regulation of the genome, an emerging theme is that these enzymes often also act by non-catalytic and/or non-epigenetic mechanisms. S2CID 7827573.Histone modifying enzymes play critical roles in many key cellular processes and are appealing proteins for targeting by small molecules in disease. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". "Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1". "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Gerhard DS, Wagner L, Feingold EA, et al."Large-scale characterization of HeLa cell nuclear phosphoproteins". Beausoleil SA, Jedrychowski M, Schwartz D, et al."Complete sequencing and characterization of 21,243 full-length human cDNAs". "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Strausberg RL, Feingold EA, Grouse LH, et al.The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". "Prediction of the coding sequences of unidentified human genes. ![]() "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". "Huntingtin's WW domain partners in Huntington's disease post-mortem brain fulfill genetic criteria for direct involvement in Huntington's disease pathogenesis".
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